Senior Research Associate, Cancer Biology

Employment Type

: Full-Time


: Miscellaneous

This is an early stage biotechnology company dedicated to the discovery and development of small molecules stabilizing the interaction between adaptor proteins and their disease-promoting client proteins.  Our academic founders are the world leaders in this novel approach and launched the company with a mission to provide new therapies for unmet needs in oncology.  This role is an opportunity to join San Francisco-based company as an early employee, bringing your scientific talent and passion to build the company.   The Role:  Senior Research Associate, Cancer Biology.  The successful candidate will have an integral role in the planning and conduct of experiments that support drug discovery efforts including:   * Conduct research to evaluate therapeutic hypotheses for candidate drug targets * Design and develop cell-based assays for compound activity and selectivity * Lead the screening of compounds for activity in cellular assays  * Design and conduct experiments to assess drug candidate mechanism of action * Evaluate activity of drug candidates in translational models of cancer * Analyze, organize, interpret and present experimental data * Collaborate and interact with colleagues in design and conduct of experimental series * Maintain clear and up-to-date experimental records and prepare study reports * May train and /or supervise Research Associates, interns, and other laboratory personnel   Senior Research Associate applicants should have the following qualifications:   * BS or MS in biology, molecular biology, cell biology, biochemistry or a related field * Minimum 5 years of experience in cancer research or drug discovery in a biotech industry setting * Demonstrated technical proficiency in mammalian cell culture and molecular cell biology * Experience with cell-based assays to measure viability, proliferation, activation, differentiation, signaling, and apoptosis. * Experience with transient transfection, Western blot, and analysis of gene expression. * Ability to work independently and collaboratively in a team environment. * Excellent record keeping and organizational skills * Strong written and oral communication skills * Ability to work independently, multi-task and manage time efficiently * Flexibility within a fast-moving start up environment * Collaborative, positive and team-oriented outlook

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