Principal Research Associate, Biology

Employment Type

: Full-Time


: Miscellaneous

Principal Research Associate, Biology Position Summary: We are seeking a highly-motivated, well-organized and laboratory-focused senior or principal research associate that will pay a key role in designing and executing cell-based assays and developing new platforms to evaluate our proprietary compounds. The successful candidate will work in a multidisciplinary team and contribute to the generation of novel therapeutics for the treatment of cancer. Position level will commensurate with experience. What you’ll do: * Run high throughput cell-based assays to support compound screening efforts * Maintain and culture multiple cancer cell lines * Develop assays to support cellular and MOA studies using molecular biology methods such as qRT-PCR, Western blotting and ELISAs. * Validate preclinical molecular data to support clinical biomarker assay development * Design research experiments under general supervision and work independently to execute experiments * Analyze and interpret scientific data under general supervision * Present data and report on project status at individual, Biology group and departmental research meetings * Maintain inventory of biology lab reagents and order general supplies * Work and communicate effectively with different CROs on specific projects, interpret, validate and report data to the team.   Requirements * BS/BA degree in molecular biology or related discipline and 2-5+ years of related experience or MS/MA degree in related discipline and 2-6 years of related experience * Expertise in mammalian tissue culture and cell-based assays to evaluate viability, protein production (western blot, ELISA), gene expression analysis (qRT-PCR) and other functional/molecular biology assays. Flow cytometry, MSD and immunofluorescence is a plus. * Prior experience in handling and processing mouse or human tissue is a plus. * Experience in high-throughput compound screening is a plus * Ability to develop, optimize and troubleshoot cell and molecular based experiments * Efficient time management and the ability to adapt to shifting priorities and timelines * Strong interpersonal skills and effective communication with cross function team members

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