IHC Senior Scientist

Employment Type

: Full-Time

Industry

: Miscellaneous



IHC Senior Scientist We are seeking a motivated and detail-oriented Senior Scientist to lead our histopathology lab for target validation  and translational research at our San Jose, CA site.    The Senior Scientist will be part of a team dedicated to developing various tissue-based technologies to drive discovery programs and enable translational biomarker strategies in multiple oncology programs. The appropriate candidate will be expected to independently execute the necessary histopathology techniques for evaluating tumor and immune cell therapeutic targets and supervise one or more RAs.   The ideal candidate will be an experienced Senior Scientist capable of leading a team. They will possess in-depth experience in validating translational immunohistochemistry (IHC) and multiplexed immunofluorescence assays, antibodies, and tissue-based special transcriptomics. He/she will also have strong communication skills, ability to work in a matrixed-based, fast paced environment, solid problem-solving abilities, and a commitment to excellence.   This role will support our target validation efforts and assessment of molecules currently in our pipeline by using immunohistochemistry (IHC), immunofluorescence (IF), in situ hybridization (ISH), microscopy and digital imaging and analysis.   The majority of responsibilities will be focused on IHC, including the development, screening, and validation of IHC antibodies, oncology indication-focused tissue procurement, sample processing and embedding (FFPE and FF), sectioning (FFPE and FF), and assay development (both manual and automated). Thorough knowledge of histology and oncology fundamentals is required and some cell culture and molecular biology experience is desirable.

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